Insulinase-like Protease 1 Contributes to Macrogamont Formation in Cryptosporidium parvum
نویسندگان
چکیده
Cryptosporidiosis is a debilitating diarrheal disease in young children developing countries. The absence of effective treatments or vaccines makes this infection very difficult to manage susceptible populations.
منابع مشابه
Local peroxynitrite formation contributes to early control of Cryptosporidium parvum infection.
In intestinal inflammation, mucosal injury is often exacerbated by the reaction of NO with neutrophil-derived superoxide to form the potent oxidant peroxynitrite. Peroxynitrite also has antimicrobial properties that aid in the killing mechanism of macrophages and neutrophils. Cryptosporidium parvum parasitizes intestinal epithelium, resulting in loss of epithelial cells and mucosal inflammation...
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The purpose of this study was to determine if the viral symbiont of Cryptosporidium parvum (CPV) sporozoites could be used as a target for sensitive detection of the parasite in food samples. Polyclonal sera specific to the recombinant viral capsid protein (rCPV40) was used in a dot blot hybridization assay to detect oocysts recovered from green onions and cilantro. Small batches of chopped gre...
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ژورنال
عنوان ژورنال: MBio
سال: 2021
ISSN: ['2161-2129', '2150-7511']
DOI: https://doi.org/10.1128/mbio.03405-20